Pyrococcus furiosus factor

There has been much discussion about the exact role microwaves play in promoting organic reactions. It is clear that microwaves can activate peptide bond rotation. This may be a factor in the observation J. Am. Chem. Soc. 2008,130, 10048) by Alexander Deiters of North Carolina State University that the rate of the hydrolysis of 24 to 25 by the P-glucosidase CelB from the hyperthermophilic archaeon Pyrococcus furiosus increased by at least four orders of magnitude under microwave irradiation. 

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