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Pyrimidines, synthesis from oximes

A general method for the synthesis of pyrimidine A-oxides from amidoximes is described. The conversion involves treatment of various carboxamide oximes 325 with 1,1,3,3-tetramethoxypropane, 2,4-pentanedione or 3-ethoxy-2-methylpropenal in the presence of CF3COOH to afford pyrimidine 1-oxides 326 (equation 141) . [Pg.279]


See other pages where Pyrimidines, synthesis from oximes is mentioned: [Pg.290]    [Pg.135]    [Pg.934]    [Pg.152]    [Pg.318]    [Pg.201]    [Pg.315]    [Pg.578]   
See also in sourсe #XX -- [ Pg.255 , Pg.279 , Pg.280 ]




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Pyrimidines, synthesis

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