Of pyrimidines, biological

Such calculations have been made also for pyrimidines of biological interest (B-60MI21302). That for uracil (5) is interesting in that a figure of -0.22 is assigned to the 5-position, compared with almost zero in pyrimidine this immediately explains the ease of electrophilic attack at the 5-position of uracil as well as the lack of nucleophilic activity at the same position. 

Some Pyrimidines of Biological and Medicinal Interest—Part II... 

SOME PYRIMIDINES OF BIOLOGICAL AND MEDICINAL INTEREST—PART III... 

SOME PYRIMIDINES OF BIOLOGICAL AND MEDICINAL INTEREST—PART III slightly active against the parasites Eperythrozon [96] and relieves symptoms of some carcinoma patients, but frequently produces hypoglycaemia, with fatty degeneration of the liver [70],... 

SOME PYRIMIDINES OF BIOLOGICAL AND MEDICINAL INTEREST—PART in octanol figures is 0-829, where n (the number of data) is 10. This is a positive, but not close, correlation. The standard error (5) is 27. 

SOME PYRIMIDINES OF BIOLOGICAL AND MEDICINAL INTEREST—PART III longer than that of (XXXII) or of carisoprodol. The toxicology is similar to that of (XXXII), with a wide safety margin. Anticonvulsive properties are similar to those of methyl phenobarbital. The substance has depressant... 

SOME PYRIMIDINES OF BIOLOGICAL AND MEDICINAL INTEREST—PART III Waals-London interaction energies confirm the fact that these pairs form the strongest associations [229, 230]. In some of the models, the H-bonded arrangement was different from that of (LIV), but this appears to be the single structure present in the natural polymer. 

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