Pyrimidines Af-oxidation

The synthetic uses of pyrimidines in the construction of non-heterocycles appear to be relatively small. While the ring opening reaction of a pyrimidine Af-oxide with phenylmag-nesium bromide has been reported to give benzaldehyde upon hydrolysis (it thus plays the same role as DMF) (67JOC3788) the Diels-Alder capabilities of the pyrimidines do, on the other hand, appear to hold considerable promise in organic chemistry. 

Pyridine and pyrimidine Af-oxides 1320-1230 7.58-8.13 m-s m N-0 str, hydrogen bonding lowers... 

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