Pyridoxamine dihydrochloride

Wilson and Harris (Merck) used the reagent to etfect the synthesis of cocarboxylase (3) from pyridoxamine dihydrochloride (1). This route proved superior to one employing phosphoryl chloride. 

Phosphorus pentodde-Phosphoric acid. Anhydrous phosphoric acid (orthophosphoric acid) is prepared by dissolving 25 g. of P Os in 33 g. of 85% phosphoric acid. - Wilson and Harris used this reagent to phosphorylate pyridoxamine dihydrochloride with phosphoryl chloride the yield whs very low. 

Pyridoxal, excited state ionization studies, 743 Pyridoxamine, excited state ionization, 743 Pyridoxamine dihydrochloride, 103... 

A mixture of palladium chloride, activated carbon, and aq. HCl prehydrogenated during 10-20 min., ice-cold water and pyridoxal oxime added, then the hydrogenation continued for 45 min. pyridoxamine dihydrochloride. Y 98.2%. M. V. Balyakina, E. S. Zhdanovich, and N. A. Preobrazhenskii,... 

Figure 9.1. Interconversion of the vitamin Be vitamers. Pyridoxal kinase, EC 2.7.1.38 pyridoxine oxidase, EC 1.1.1.65 pyridoxamine phosphate oxidase, EC 1.4.3.5 and pyridoxal oxidase, EC 1.1.3.12. Relative molecular masses (Mr) pyridoxine, 168.3 (hydrochloride, 205.6) pyridoxal, 167.2 pyridoxamine, 168.3 (dihydrochloride, 241.1) pyridoxal phosphate, 247.1 pyridoxamine phosphate, 248.2 and 4-pyridoxlc acid, 183.2.

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