Pyridine nucleotide-dependent dehydrogenase

Pyridine nucleotide-dependent dehydrogenases (ed. H. Sund). Berlin—Heidelberg—New York Springer 1970. 

Alcohol dehydrogenase is also obtained from yeast. Yeast alcohol dehydrogenase (YADH) was the first pyridine nucleotide-dependent dehydrogenase to be crystallized by Negelein and Wulff in 1937.1342 YADH is a tetramer of molecular weight 140000-150000. The amount of zinc determined varies,1343 but there are strong indications that the subunits of YADH and LADH have similar structures, including the presence of two zinc atoms. 

C. I. Branddn, E. Zeppezauer, T. Boiwe, C. Sdderlund, B. O. Soderbeg and B. Nordstrom, in Pyridine Nucleotide Dependent Dehydrogenases , ed. H. Sund, Springer-Verlag, Berlin, 1970, p. 133. 

Theorell, H. (1970) in H. Sund (Ed.), Pyridine Nucleotide-Dependent Dehydrogenases, Springer, Berlin, pp. 121-126. 

S. F. Velick tn Pyridine Nucleotide-Dependent Dehydrogenases (H. Sund, ed.), p. 57. Springer-Verlag, Berlin and New York, 1970. 

Jr., G. Zanetti, and S. Ronchi, in Pyridine Nucleotide-Dependent Dehydrogenases ... 

Eisele, B., Wallenfels, K. Pyridine nucleotide-dependent dehydrogenases (ed. H. Sund), p. 91. Berlin - Heidelberg - New York Springer 1970. 

The choice of the indicator electrode is largely determined by the species involved in the sensing reaction. Oxygen and H2O2, which are the cosubstrate and product of oxidases, as well as NAD(P)H—the cosubstrates of about 300 pyridine nucleotide-dependent dehydrogenases—can be determined amperometrically. Based on this principle, many enzyme sensors of the first generation have been developed and commercialized (see section 17.4 and table 17.2). 

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