Alkyl-Pyridines

Table 2. Physical Properties of Pyridine, Alkyl-, and Alkenylpyridine Derivatives ...

NQR, 2, 125 Pyridines, acetylalkyl-alkyl deacetylation, 2, 301 Pyridines, acetyltrimethyl-synthesis, 2, 470 Pyridines, acyl-conformation, 2, 162 reactions, 2, 337 Pyridines, alkenyl-ozonolysis, 2, 334 reactions, 2, 334 Pyridines, alkenyldihydro-disproportiation, 2, 62 Pyridines, alkyl-... 

Pyrrolopyridines — see Indolizines Pyrrolo[l,2-a]pyridines — see Indolizines Pyrrolo[2,3]pyridines alkylation, 4, 504 synthesis, 4, 528... 

Use of the urea-hydrogen peroxide complex and /V,/V -bis(TMS) urea provides an improved method126 for the preparation of bis(TMS) peroxide, TMSOOTMS. In the presence of Fe(m)(picolinic acid)3, bis(TMS) peroxide carries out selective oxidation of alkanes to ketones by a non-radical mechanism. The Fe(III)-Fe(IV) manifold is believed to be responsible127. On the other hand, using FeCU in pyridine, alkyl chlorides are formed through a radical mechanism. Here, the Fe(n)-Fe(IV) manifold has been proposed128. 

Substituted furans are awkward to make but 3-hydroxymethylfuran 207 is available commercially and is converted into the corresponding bromide 205 with PBr3 in pyridine. Alkylation of a vinyl cuprate with this reactive alkyl bromide was used here. 

In principle, the interaction of a phosphorus(III) ester with an co-haloalkylamine should lead to an (co-aminoalkyl)phosphonic diester or a phosphinic acid analogue (Scheme 11). Such examples in the classical Michaelis-Arbuzov mould have been widely reported, but success in their outcome depends on the relative nucleophilicities of nitrogen and phos-phorus(III) centres towards the displacement of halogen. The interaction of triethyl phosphite and a halogen-substituted tertiary amine, such as 2-chloroethyldiethylamine, does not lead to a phosphonic diester, and in this particular case the product is a piperazinium diquaternary salt. However, successful Michaelis-Arbuzov reactions have been carried out between the bis(bromomethyl)phthalazines 130 (to both the mono- and di-phosphonic acid stages) and the series of [co-(2-cyano-4-pyridine)alkyl]phosphonic diesters 132 (n = 1-4) have been prepared from the 4-pyridinealkyl bromides 131 as precursors to the phosphonoalkylpiperidinecarboxylic acids 133 . ... 

Quantum yields of formation of OaC Ag) obtained by irradiation of benzene solutions of various flavonoids, and by irradiation of oxodiperoxo-molybde-num(VI) complexes of the type (L-L)MoO(02>2 (L-L = 2-(l-alkyl-3-pyrazolyl)-pyridine, alkyl = Bu, n-octyl, n-octadecyl L-L = 2-(3-n-octyl-2-... 

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