Purkinje cells adrenergic receptors

Fig.78. A. x28 and B. x42 power photomicrographs of autoradiographs of iodocyanopindol ( ICYP) binding to adrenergic beta receptors in rat cerebellar cortex illustrating the high density of silver grains in the molecular layer and patches of increased receptor density over the Purkinje cell layer, m, molecular layer g, granule cell layer. (C) shows the patches at x 40 magnification with dark-field illumination. Sutin and Minneman (1985).

Polyclonal antibodies which recognize domains of the y82 adrenergic receptor other than the NA-binding site, immunoreact with distal segments and dendritic spines of rat Purkinje cells. Immunoreactivity is present throughout the dendritic cytoplasm and accumulates at the dendritic membrane, opposite synaptic clefts (Strader et al.,... 

---