Pulmonary alveolar proteinosis lung transplantation

Respiratory Pulmonary alveolar proteinosis is a rare complication of treatment with sirolimus but has been reported in a 49-year-old female kidney transplant recipient [126 ]. A biopsy showed intact lung parenchyma and macrophages among alveoli filled with PAS-positive eosinophilic material which also stained positive for... 

Santamaria F, Brancaccio G, Parenti G, et al. Recurrent fatal pulmonary alveolar proteinosis after heart-lung transplantation in a child with lysinuric protein intolerance. J Pediatr 2004 145(2) 268-272. 

Gal AA, Bryan JA, Kanter KR, et al. Cytopathology of pulmonary alveolar proteinosis complicating lung transplantation. J Heart Lung Transplant 2004 23(1) 135-138. 

Cooke KR, Nishinakamura R, Martin TR, et al. Persistence of pulmonary pathology and ahnormal lung function in IL-3/GM-CSF/IL-5 heta c receptor-deficient mice despite correction of alveolar proteinosis after BMT. Bone Marrow Transplant 1997 20(8) 657%62. 

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