Pseudo-trisaccharides synthesis

In the synthesis of a Sialyl Lewis X analogue, l,4,5,6-tetradeoxy-l,4-imino-D-ido-hexitol (for synthesis see Section 1.3.1) was a-L-fucosylated at the less hin> dered (C-2) hydroxyl, then p-D-galactosylated at 0-3 to produce a non-sulfated precursor to the pseudo-trisaccharide 137. ... 

A synthesis of 6-deoxy-6-hydroxyamino- -D-glucopyranoside from the corresponding 6-aminosugar by the sequence of oxidation with hydrogen peroxide - sodium tungstate to the oxime followed by cyanoborohydride reduction was copied in a synthesis of the pseudo-trisaccharides 6 -N-hydroxykanamycin A and 6 -N-hydroxydibekacin from the corresponding parent antibiotics, but the products were... 

The same group has also reported an analogous synthesis of the pseudo-trisaccharide adiposin-1 (43). ... 

Reviews have appeared on the synthesis of aminoglycoside antibiotics, and on the formation of new aminocyclitol antibiotics by mutants of amino-cyclitol-producing organisms fed with aminocyclohexanol or related subunits. The structures of eight minor components of the nebramycin complex elaborated by Streptomyces tenebrarius have been elucidated besides neamine and related pseudo-disaccharides, the new components are pseudo-trisaccharides related to kanamycin B, and the 3 -hydroxy analogue of the principal component of the complex, apramycin (see Vol. 10, p. 130). ... 

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