Protonolysis demercuration

The former cannot be considered a good synthetic method because a mixture of reaction products is usually obtained. The protonolysis of organomercury compounds has been extensively studied from a mechanistic standpoint but has found little synthetic utility except for isotopic labelling of organic molecules. Reduction is the most useful method for the demercuration of organomercury compounds, particularly of solvomercurials in the solvomercuration-demercuration reaction, and a lot of reductants are used for this purpose. 

The present review considers recent advances in mercury-hydrogen interchange by protonolysis and reducing agents, and especially metal hydride demercuration. 

The importance of organomercurials in organic synthesis is due in large part to the valuable solvomercuration-demercuration reaction. As the reaction of proton acids with solvomercurated products derived from alkenes leads back to the alkene, protonolysis has in this procedure little synthetic utility. 

---

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

---