Proton pump inhibitors observational studies

Observational studies Stress ulcer prophylaxis with ranitidine has been associated with an increased risk of ventilator-associated pneumonia. The use of proton pump inhibitors has also been linked to an increased risk of community-acquired pneumonia, and pantoprazole is commonly used in stress ulcer prophylaxis. In a retrospective observational study the database of a cardiothoracic surgery unit was used to identify all patients who had received stress ulcer prophylaxis with pantoprazole or ranitidine 887 patients met the inclusion criteria [66% Nosocomial pneumonia was... 

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