Proton Density Weighted MRI

While these imaging modalities are sensitive to cell type, the combination of T, T and proton density are not specific to cell type or the type of alteration in normal cell physiology. Improved specificity can be obtained by combining these MRI scans with other types of information including clinical manifestations of disease, other neuroimaging scans and advanced analytical methods to improve diagnostic accuracy. 

Recent studies have also shown that neuronal depolarization will cause increases in Tj and T. T was shown to increase by 13% while T2 increased by 88% at 1.5 T in a rat model of spreading depression (Stanisz et al., 2002). While 

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