Proteinuria in membranous nephropathy

Size selectivity is probably caused by the mesh of glomerular basement proteins, which effectively restricts the passage of larger proteins with molecular weight of more than 150 kDa. Loss of size selectivity is probably the main cause of nonselective proteinuria in membranous nephropathy (SI3). 

Proteinuria in membranous nephropathy is nonselective and it is believed to be caused by the loss of size selectivity (C4). 

Bazzi C, Petrini C, Rizza V, Arrigo G. Beltrame A, Pisano E, D Amico G. Urinary excretion of IgG and P-1 -microglobulin predicts clinical course better than extent of proteinuria in membranous nephropathy. Am J Kidney Dis 2001 38 240-248. 

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See also in sourсe #XX -- [ ]

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