Proteins ODNA complex

The number of the NOE and other constraints (total constraints = 3982) obtained for the structure calculation is given in Table IV. As in the cases of the holorepressor 10) and the trp repressor-consensus ODNA complex (i). the distribution of the NOEs in the protein is not uniform, with fewer NOEs near and within helix D. There are on the average 15 NOEs per residue in the core, only 5 NOEs per residue in helix D and 12 NOEs per residue in helix E. The distribution of NOEs in the DNA is also not uniform. Comparing Table I and II, it can be seen that there are fewer NOEs in the complex than in the mtr ODNA control. 

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