Proteins Binding of metals

Circular dichroism Secondary structure of proteins, interaction between ligands and proteins, binding of metals at active sites in enzymes 1 )... 

A number of the amino acids in Table 1 have polar side groups and hence the potential of becoming tridentate. As will be seen later it is these third sites which become important in protein binding of metal ions. 

Koizumi, S., Suzuki, K., Ogra, Y., Yamada, H. and Otsuka, F. (1999) Transcriptional activity and regulatory protein binding of metal-responsive elements of the human metallothionein-IIA gene. EurJ. Biochem., 259, 635-642. 

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