Protein synthesis cont mechanism

Cell sap contains a specific phosphoprotein phosphatase (P) which dephosphoiylates protein 67, eIF-2 and several other dsRNA-dependent phosphorylated proteins (5). The protein phosphatase P is separated from PK-i on DEAE-cellulose and elutes at 25O1DM KCl. As shown in Figure 5> P stimulates mengo RNA translation in interferon-treated cell extracts (SlO-int) supplemented with dsRNA, but not in control cell extracts (SIO-cont). This suggests a regulatory mechanism which controls the level of PK-i dependent inhibition of protein synthesis. 

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See also in sourсe #XX -- [ , , ]

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