Paralogous proteins

S Hcnikoff, EA Greene, S Pietrokovski, P Bork, TK Attwood, L Hood. Gene families the taxonomy of protein paralogs and chimeras. Science 278 609-614, 1997. 

Darnell JC, Fraser CE, Mostovetsky O, Darnell RB. Discrimination of common and unique RNA-binding activities among fragile X mental retardation protein paralogs. Hum Mol Genet 2009 18 3164-77. 

Alitalo A, Mcri T, Lanldnen H et al. Complement inhibitor hictor H binding to Lyme disease spirochetes is mediated by inducible expression of multiple plasmid-encoded outer surface protein paralogs. J Immunol 2002 169(7) 3847-3853. 

Detailed analyses of expansions of paralogous proteins are important not only from a diagnostic perspective (identifying members of gene families unique to specific organisms), but also from a therapeutic perspective (developing vaccines and... 

Edman degradation 98 proteases 99 proteome 101 lateral gene transfer 107 homologous proteins 107 homolog 107 paralog 107 ortholog 107 signature sequence 109... 

C Goffin, JM Ghuysen. Multimodular penicillin-binding proteins an enigmatic family of orthologs and paralogs. Microbiol Mol Biol Rev 62 1079-1093, 1998. 

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