Protein molecular weights, brush border

Table 2.1. Molecular weights of proteins and glycoproteins associated with the tegumental brush border of Hymenolepis diminuta. (Data from Knowles Oaks, 1979.) (See also Figs. 6.3 and 6.6)...

Fig. 6.6. A fluorograph of the major polypeptides synthesised in the brush border of adult Hymenolepis diminuta, following their separation by two-dimensional PAGE the apparent molecular weight (Mr) and isoelectric point (pi) of each protein are also shown. (After Atkinson Podesta, 1982.)...

Figure 5. SDS-acrylamide gel electrophoresis of brush border membrane proteins from rats of adequate zinc status (0), following a 4-day zinc depletion (4), and following an 8-day zinc depletion (8). Proteins migrating with approximate molecular weights of 63,000 and 45,000 daltons are more apparent after 4 and 8 days of dietary zinc restriction.

Functionally, urinary markers of Cd nephrotoxicity can be classified into 3 groups (1) Cd and Cd-binding proteins such as MT, (2) low-molecular-weight proteins, and (3) proteins and enzymes derived from the brush border, intraceUular organelles or the cytosol of proximal tubule epithelial cells. 

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