Protein dynamics hydrogen-deuterium exchange mass

Hamuro, Y. Coales, S.J. Southern, M.R. Nemeth-Cawley, J.F. Stranz, D.D. Rod, G.P. Rapid analysis of protein structure and dynamics by hydrogen/deuterium exchange mass spectrometry. J. Biomol. Tech. 2003,... 

Elucidation of the dynamics of protein conformation and the contact surfaces in protein interactions with other proteins, nucleic acids, etc., is important to the understanding of protein function. Hydrogen/deuterium exchange (HDX, H/D, H-D) is a mass spectrometric strategy to obtain such information. 

Higher-Order Structure and Dynamics of FK506-Binding Protein Probed by Backbone Amide Hydrogen/Deuterium Exchange and Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry... 

Zhang, Z., Li, W., Li, M., et al. (1997) Higher-order structure and dynamics of EK506-binding protein probed by backbone amide hydrogen/deuterium exchange and electrospray ionization Eourier transform ion cyclotron resonance mass spectrometry. Tech Protein Chem VIII, 703-713. 

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