Protein Crystallography in Drug Discovery

Babine RE, Abdel-Meguid SS. Protein crystallography in drug discovery (Vol. 20 of Mannhold R, Kubinyi H, Folkers G, editors. Methods and Principles in Medicinal Chemistry). Weinheim Wiley-VCH, 2004. 

Jhoti, H. (2004). High-throughput crystallography. In Protein Crystallography in Drug Discovery, Babine, R. E. and Abdel-Meguid, S.S., eds. WUey-VCH Verlag, Weinheim. 

Waugh, S. M. and Fletterick, R. J. (2004). Crystalhzation and analysis of serine proteases with ecotin. In Protein Crystallography in Drug Discovery. Methods and Principles... 

Protein Crystallography in Drug Discovery Edited by R. E. Babine and S.S. Abdel-Meguid... 

The objective of this book is to provide a forward looking overview of the use of protein crystallography in drug discovery. It has been organized so that the early chapters review and describe some mature and emerging topics that would fall under the traditional structure-based desigrf umbrella, the middle chapters provide focused accounts of specific works, and the final chapters delve into new and fertile areas of research. This book does not attempt to be comprehensive thus the final lineup of chapters was a compromise between the interests of the editors and the willingness of the authors to contribute a chapter. 

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