Protein crystallization growth rate determination

As in any crystallization, the production of protein crystals requires bringing the protein into a supersaturated liquid state. The degree of supersaturation determines the rate of nucleation as well as crystal growth rate. Each of these phenomena are... 

The study of conditions that optimize the association of proteins in solution guides the design of protocols for the formation of large crystals that are amenable to analysis by the X-ray diffraction techniques discussed in Chapter 11. It is important to characterize protein dimerization because the process is considered to be the rate-determining step in the growth of crystals of many proteins. Consider the variation with ionic strength of the rate constant of dimerization in aqueous solution of a cationic protein P ... 

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