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Protein-coding genes open reading frame

The EDITSEQ application allows you to manually enter DNA or protein sequence information into your computer. This application has several features that make it useful to the research scientist. First, it can identify open reading frames (possible gene sequences) within a DNA sequence. Second, it can provide the percent base composition (A,G,C,T), the percent GC, the percent AT, and the melting temperature of the entire sequence or a small subset of that sequence. Third, EDITSEQ can translate a nucleotide sequence into a protein sequence. Finally, the application is capable of translating or reverse translating a nucleotide sequence of interest using codes other than the standard genetic code. [Pg.402]

The disease is caused by a CAG expansion in the SCA6 gene at chromosome 19pl3, which codes for the aia-voltage-dependent calcium channel subunit (Zhuchenko et al., 1997). Six isoforms of this protein have been described. The CAG repeat is within the open reading frame and is predicted to encode Qn domains in... [Pg.333]


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Gene protein-coding

Open reading frame

Reading frame

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