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Protective mechanisms against cellular toxicity

The physiological result of the binding of the non-essential lanthanide and actinide metals to albumin, or transferrin, in the blood plasma may well be that the metals are held in a form in which they are virtually unable to penetrate the cell membrane in ionic form thus limiting cellular uptake and also the ability to cause harmful effects by interaction with essential enzymes or other proteins. Thus for the non-essential f elements, protein binding may be regarded as part of a protective mechanism against chemical toxicity,... [Pg.610]

It is assumed that for health effects other than cancer, a threshold or non-linear dose-response relationship exists. This is based on known compensatory and adaptive mechanisms that protect against the toxic effects of childhood exposures, as well as on repair mechanisms at the molecular, cellular, and tissue... [Pg.222]

The Keapl-Nrf2 Cellular Defense Pathway Mechanisms of Regulation and Role in Protection Against Drug-Induced Toxicity... [Pg.233]


See other pages where Protective mechanisms against cellular toxicity is mentioned: [Pg.912]    [Pg.282]    [Pg.862]    [Pg.863]    [Pg.17]    [Pg.132]    [Pg.204]    [Pg.302]    [Pg.309]    [Pg.114]    [Pg.213]    [Pg.236]    [Pg.340]    [Pg.255]    [Pg.309]    [Pg.606]    [Pg.309]    [Pg.70]    [Pg.75]    [Pg.202]    [Pg.377]    [Pg.43]    [Pg.620]    [Pg.182]    [Pg.345]    [Pg.106]    [Pg.254]    [Pg.274]    [Pg.246]    [Pg.1164]    [Pg.348]    [Pg.95]    [Pg.1164]    [Pg.214]    [Pg.437]    [Pg.96]    [Pg.363]    [Pg.347]    [Pg.352]    [Pg.1907]    [Pg.366]    [Pg.17]    [Pg.214]    [Pg.97]    [Pg.379]    [Pg.62]    [Pg.67]    [Pg.94]   
See also in sourсe #XX -- [ Pg.230 , Pg.231 , Pg.232 , Pg.233 ]




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Cellular mechanism

Cellular toxicity

Mechanical protection

Toxic mechanisms

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