Prostaglandins semi-synthesis

Lipid chemistry contains many instances of semi-synthesis in the chemistry of the fatty vitamins, prostaglandins and leukotrienes, the phospholipids, and the glycerides with their structural relatives. 

The lactone A was also used as starting material in the synthesis of the primary prostaglandins via an allylic substitution-semi-pinacolic rearrangement sequence (Ref. 2). 

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