Propionyl fluoride

Polyethylene glycol (molecular weight, 300-6(W) can aid in the displacement of activated halogen by fluorine. Propionyl chloride is converted to propionyl fluoride with potassium fluoride and polyethylene glycol in acetonitrile [63] Treatment of benzyl chloride with a mixture of potassium fluoride and potassium iodide for 5 h in acetonitrile containing polyethylene glycol 200 gives benzyl fluoride in 62% yield [64],... 

Propanol with magnesium in reduction of chlorobenzene, 47, 104 Propionyl fluoride, 46, 6 n Propylamine, 46, 85 n Propylhydrazine, 46, 85 C ( Propyl) N phenylmtrone, genera tion from phenylhydroxylamme and n butyraldehyde, 46, 97 Purification of tetrahydrofuran (Warning), 46,105 4H Pyran 4-one, 2 6 dimethyl 3,5 diphenyl, 47, 54... 

Dehydrohalogenations have been used for the preparation of many polyfluorinated compounds containing additional functionalities. Hydrogen fluoride is eliminated from 2//-tetrafluoro-propionyl fluoride (1) to give trifluoroacryloyl fluoride (2).87... 

The chemistry of perfluoro(2-methyloxirane) (hexafluoropropylene oxide) has been comprehensively reviewed, including its isomerization to hexafluoroacetone or propionyl fluoride.28 The rearrangements of polyfluorooxiranes with Lewis acids have been reviewed by Krespan and Petrov.29 Fluoride ion and other Lewis bases rearrange tetrafluorooxirane and monosubstituted perfluorooxiranes to acyl fluorides, and symmetrically disubstituted perfluorooxiranes to ketones (Scheme 9).30... 

Perfluoroalkylvinylethers, such as perfluoropropylvi-nylether (CF2=CF-0-C3F7, CAS number 1623-05-8) are synthesized according to the steps shown in Fig. 2. There are also electrochemical processes for the production of perfluoro-2-alkoxy-propionyl fluoride. ... 

HFPO is reacted with a perfluorinated acylfluoride to produce perfluoro-2-alkoxy-propionyl fluoride ... 

Perfluoro 2-aIkoxy-propionyl fluoride is reacted with the oxygen containing salt of an alkali or alkaline earth metal at an elevated temperature which depends on the type of salt. Examples of the salts include sodium carbonate, lithium carbonate, and sodium tetraborate ... 

A cyclic lactone is formed by the reaction of 1,4 diiodo-perfluorobutane with oleum (see Fig. 47). The addition of methanol to the lactone gives selectively 3-methoxycar-bonyl perfluoro-propionyl fluoride, to which hexafluoropropylene oxide is added. After copolymerization with tetrafluoro ethylene, the acid fluoride group is converted to a perfluorovinyl group by pyrolysis. 

Potassium oleate 9098 Propionyl fluoride 9171 4(l/l)-Pyrimidinone, 5-butyl-2- ... 

Direct fluorination of propionyl fluoride and acetic anhydride has failed to yield the corresponding fluorocarbon derivatives the former sub strate gave a complex mixture of fluorinated propionyl fluorides, and hy drolysis of the product from the latter yielded a mixture of monofluM o and difluoro-acetic acids. 

Propionyl chloride or anhydride cooled, stirred, and treated with anhydrous HF, allowed to warm to room temp., stored 2 hrs. at this temp., then treated with anhydrous NaF to remove excess HF propionyl fluoride. Y 89.0 and 91.5% respectively. F. e. s. G. A. Olah and S. J. Kuhn, J. Org. Ghem. 26, 237 (1961). 

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