Propio nitril

M TEAH/propio-nitrile nitrome sitylene -35 0.029 cv 92Saf... 

Porasll C 3-Hydroxy- propio- nitrile (3.60) Medium 135 Low molecular weight hydrocarbons, aromatics, and oxygenated compounds. 

This hydrodimerization reaction forms adiponitrile, which is a precursor for nylon. However, the two-electron reduction of this reactant results in propio-nitrile, an undesired product ... 

The use of haloalkenes or halohydrins in Ritter-type reactions has resulted in the development of an oxazoline (105) synthesis85 yields are 60-70%. The formation of 2-ethyl-4,4-dimethyl-5,6-dihydro-4Zf-1.3-oxazine (106)55 from 1-chloro-3-methyl-2-butene and propio-nitrile in the presence of sulfuric acid has a similar basis. 

Diethylamine (355 g., 5.0 moles) is added with stirring and cooling to 500 g. (9.5 moles) of acrylonitrile. The addition requires about 10 minutes, and the mixture is refluxed for 30 minutes longer and allowed to stand overnight in the refrigerator. Distillation gives a 93% yield of -diethylaminopropionitrile, b.p. 104-106°/35 mm. pressure, 1.4352. See also preparation of )3-(di-n-amylamino)-propio-nitrile (p. 98). 

Hydrocyanic acid adds to bis(dimethylamino)ethylene (516) to give 2,2-bis(dimethylamino)propio-nitrile (517 Scheme 94).28,29,35,977 gy deavage of aminal esters with acyl cyanides or hydrocyanic acid a,a-diaminonitriles (518) are accessible trisaminomethanes have also been cleaved by HCN to give nitriles (518). 

Reaction intermediates such as radicals, carbonium ions, carbanions, cation and anion radicals, dications and dianions can be produced. For example, six reversible redox reactions of 9,9 -bianthryl-10,10 -dicarbonitrile in 0.1 M Bu4NPFg/propio-nitrile solution yield a spectrum of products ranging from the tetra-anion to the dication... 

Reduction of nitriles—Aceto-nitrile—n-Propio-nitrile. [Aromatic nitriles—Benzo-nitrild —Benzyl-cyanide.].46-47... 

Cyanation. The addition of nitrile functionalities to molecules is a viable route for the introduction of carbonyl derivatives. An example of this approach can be seen in the Lewis base-catalyzed cyanomethylation of benzaldehyde with (trimethylsilyl)propio-nitrile. The Lewis base catalyst activates the Si-C bond of (trimethylsilyl)propionitrile, allowing the subsequent attack at the target aldehyde center, providing the substituted benzylic alcohol in good to excellent yields. However, upon treatment of the same starting materials with both Lewis base catalyst and TBAT, overall yields declined (eq 20). 

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