2-Propanone oxime

Dimethoxyphenyl)-2-propanone oxime thus prepared boiled at about 165-175°C at 0.6 mm pressure. Analysis showed the presence of 7.23% of nitrogen, compared with the calculated amount of 6.69%. 

A solution of 151 grams of 1-(3, 4 -dimethoxyphenyl)-2-propanone oxime in 200 cc of absolute ethanol is treated with 5 grams of Raney nickel catalyst and ammonia in an autoclave at about 25 atm of pressure and at 75 -100°C. The reduction is complete in about one-half hour and the reaction mixture is filtered and fractionated under reduced pressure to recover the a-methylhomoveratrylamine formed by the reduction. a-Methylhomoveratryl-amine thus prepared boiled at 163°-165°C at 18 mm pressure. 

Acetoxime or Acetone Oxime(2-Propanone Oxime or Dimethyl Ketoxime), mw 73.00,... 

Some simple oximes have been shown to act as N—O bidentates by side-on coordination of the oxime groups alone. The reaction of acetone with a hydroxylamido complex of molybdenum results in this bonding form for 2-propanone oxime.64,243 The N—O and C—N bond lengths indicate single and double bond character respectively. The reaction was related to the prebiotic formation of HCN from formaldehyde and hydroxylamido-Mo chelates. A similar form of bonding for this ligand was concluded with some fluorotungstate(IV) complexes.65... 

A mixture of 150 grams of l-(3, 4 -dimethoxyphenyl)-2-propanone and 70 grams of hydroxylamine hydrochloride in 125 cc of water is stirred while a solution of 51.3 grams of sodium carbonate in 150 cc of water is added over the course of 15 minutes, and while maintaining the reaction mixture at 30°-40°C. The reaction mixture is stirred for an additional two and one-half hour period at room temperature, and is then diluted with an equal volume of water and extracted three times with 300 cc portions of ether. The combined ether extracts are washed with water, dried over anhydrous magnesium sulfate, and the ether is distilled off. The residue, comprising l-(3, 4 -dimethoxyphenyl)-2-propanone oxime, may be purified by fractional distillation in vacuo. 

The presence of ammonia may depress the formation of a secondary amine, and quite high yields of primary amines have often been obtained with ketoximes over Raney Ni in the presence of ammonia, as seen in the hydrogenation of l-(4-ethoxy-3-methoxyphenyl)-2-propanone oxime (eq. 8.15)24 and 3,3-dimethyl-l-indanone oxime,25 where the corresponding primary amine was obtained in 95 and 92% yields, respectively. 

Reaction of phosgene with the anti isomer of 1-amino-1-phenyl-2-propanone oxime gives l-hydroxy-5-methyl-4-phcny -3-iraidazolin-2-one in 25% yield [49]. A review of A -oxide formation has appeared recently [50], and discussions of other approaches to the compounds are found in Section 4.1 and Chapter 5. 

Lindeke, B., E. Anderson, G. Lundkvist, H. Jonsson, and S.O. Eriksson (1975). Autoxidation of N-hydroxyamphetamine and N-hydroxyphen-termine The formation of 2-nitroso-l-phenyl-propanes and l-phenyl-2-propanone oxime. Acta Pharm. Suec. 12, 183-198. 

Propanone oxime 2-Propanone phenylhydrazone Propanoyl ohloride... 

Dimethoxyphenyl)-2-propanone oxime thus prepared boiled at about 165-175°C at... 

Also, in a closely related study, a similar sol-gd synthetic pathvray was used to prepare silica gel supported ionic liquid deoximation catalysts from carboxylic acid-functionalized ionic liquids [85]. Here various aryl and alkyl oximes were converted into the corresponding 0x0 compounds with high conversions (up to 94%) and excellent selectivity (>99%) in aqueous acetone at room-temperature by coproduction of 2-propanone oxime. TONs of up to 200 h obtained with the SILC were about four times higher than the TONs obtained using pure ionic liquids as catalysts. 

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