Profile-centric

Several shape descriptors are defined within more general approaches to - molecular descriptors. This is the case of - Kier shape descriptors, -> shape profiles, -> shadow indices, -> WHIM shape descriptors, - Sterimol shape parameters L/Bj and B1/B5, molecular - periphery codes, and -> centric indices. Other approaches to the study of molecular surface and shape are Mezey 3D shape analysis and Hopfinger - molecular shape analysis. -> Triangular descriptors have also been used to characterize molecular shape to search for similarities among molecules. 

Martens L, Van Damme P, Van Damme J, et al. (2005). The human platelet proteome mapped by peptide-centric proteomics a functional protein profile. Proteomics. 5(12) 3193-5204. 

The graphical user interface must allow role-centric subsets according to specialized user profiles, like CAD engineer, PLM data manager, controller, project manager. A one-size-fits-all approach tends to be too heavyweight for the majority of the users and will reduce the number of potential or satisfied users. 

The effect of thickness of mold copper plates on deformation of hot surface centricities is shown in Figure 3. The maximum occurs in position 100 mm below meniscus in wide face, while two peaks appear in narrow face including not only below meniscus, but also at copper-nickel boundary. The deformation is increased with thickness of copper plates and greater thickness leads to significant increment. The maximum deformations are promoted 0.03 mm and 0.06 mm in wide face and 0.03 mm and 0.05 mm in narrow face when thickness of copper plates is increased from 30 mm to 35 mm and from 45 mm to 50 mm, reqtectively. The high profile curvature in meniscus and near water slot terminals reveals that primary cooling and heat flux have greater impact on deformation of copper plates. However, property difference of copper and nickel has little effeet on deformation, and a small protrusion appears at copper-nickel boundary with thin eopper plates and oiily becomes apparent with thickness of 45 mm or more. 

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