Products Based on Oxidative Deamination or Transamination

Products Based on Oxidative Deamination or Transamination Both reactions give the corresponding keto acid. Oxidative deamination has been studied by, e.g., Stumpf and Green (839). For cases of trans- 

Thus the following pathways have been demonstrated in a Vibrio species (167)  

Reduction of the pyruvic acid would give the lactic acid (214, 502), and dehydration of this would give the acrylic acid (p-coumaric acid from tyrosine (e.g., 391) and cinnamic acid from phenylalanine). However, the acrylic acid derivative might be formed directly from the amino acid (c/. the direct conversion of histidine to urocanic acid). Reduction of the acrylic acids might be the origin of the propionic acid derivatives sometimes encountered (e.g., 100). 

Tyrosine is converted to phenol by an enzyme, /3-tyrosinase, studied especially by Japanese workers (456, 654, 658, 879). The enzyme, which has been partially purified, is inhibited by carbonyl reagents and is dependent on pyridoxal phosphate. The reaction is mechanistically probably (593) very similar to the tryptophanase reaction and is discussed when considering the function of pyridoxal phosphate (p. 91). 

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