Product of oxidative coupling

A similar phenomenon was observed for 3-amino- and5-amino-4-iodopyrazoles. The anomalous reaction in which the products of oxidative coupling of terminal acetylenes (up to 90%) are present along with the products of deiodination (up to 90%) has been described for the first time [99JCS(P1 )3713] and will be considered below in the part related to cross-coupling of 4-iodopyrazoles. 

A minor constituent of P. somniferum is the aporphine alkaloid isoboldine (Figure 6.58). Other species of poppy, e.g. Papaver orientale and P. pseudoorientale, are known to synthesize aporphine alkaloids as principal constituents rather than morphinan structures. (Aj-Isoboldinc is readily appreciated to be the product of oxidative coupling of (5)-reticuline, coupling ortho to the phenol group in the tetrahydroisoquinoline, and para to the phenol of the benzyl substituent... 

It should be noted that the composition of the product of oxidative coupling of 2,6-disubstituted phenols depends on the type of substrate [131]. For instance, the... 

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