Procymidone, fungicide

Sztejnberg, A., and Jones, A.L. 1978. Tolerance of the brown rot fungus Monilinia fructicola to iprodione, vinclozolin and procymidone fungicides. (Abstr.) Phytopathol. News 12 187. 

While the fungicides Folpet , Captan , and Captafol are forbidden in German vineyards, against B. cinerea, vinclozolin (Ronilan) 99, iprodione (Rovral) 100, and procymidone (Sumisclex) 101 are considered safe to use (89MI220) triadimefon (Bayleton) 102 is used against Oidium. 

Ostby J, Kelce WR, Lambright C, Wolf CJ, Mann P, Gray LE Jr (1999) The fungicide procymidone alters sexual differentiation in the male rat by acting as an androgen-receptor antagonist in vivo and in vitro. Toxicol Ind Health, 15(1-2) 80-93. 

This group of fungicides consists of vinclozolin, iprodione, and procymi-don. Only procymidone acts systemically however, vinclozolin and iprodione both exhibit protective and curative activities. 

Solid-Phase Microextraction (SPME). Coupled with GC/ MS, SPME was proposed for analysis of the insecticides lindane, para-thion, carbaryl, malathion, endosulfan, methoxychlor, and methida-thion, procymidone, vinclozoline, folpet, and captan (fungicides), and the herbicides terbuthylazine, trifluralin, and phosalone in wine (Vitali... 

Figure 9.5. The El fragmentation spectra of dicarboximide fungicides vinclozolin, iprodione, procymidone, and of (3,5-dichlorophenyl)hydantoin (the iprodione degradation product) recorded by stir bar sorptive extraction and thermal desorption-GC/ MS analysis (SBSE-TD-GC/MS). (Reprinted from Journal of Chromatography A, 928, Sandra et al., Stir bar sorptive extraction applied to the determination of dicarboximide fungicides in wine. p. 121, Copyright 2001, with permission from Elsevier.)...

Procymidone, N-(3,5-dichlorophenyl)-1,2-dimethyl-cyclopropane-1,2-dicarbox-imide (27), is a fungicide with moderate systemic action (Fujinami et a/., 1969). The active substance is a white crystalline material stable to the action of light, heat and humidity. It is slightly soluble in water. It is moderately toxic to mammals, the acute oral LDjo for rats being 6800 mg/kg. It is not toxic to fish or bees. 

Considerable interest is given nowadays to the possibility of using natural products as parasiticides in agriculture to replace or enhance phytochemical products, because of the serious environmental problems caused by the often indiscriminate use of pesticides. Massive use of synthetic fungicides against parasites has led to the appearance of strains which are resistant to both the dicarboximide derivatives (iprodione, procymidone, vinclozolin [64-65] and the benzimidazoles (benomyl, carbendazim, thio-phanates, etc.) [66-67] making it much more difficult to control the pathogens. 

Pesticide residues (dinoseb, pirimicarb, procymidone, pyrifenox, pyrimethanil, and thiabendazole) in peaches and nectarines Fungicide residues (procymidone and thiabendazole) in apples, grapes, oranges, pears, strawberries, and tomatoes Pesticides and metabolites (naphthalene acetamide, carbaryl, 1-naphthol, thiabendazole, and carbendazime) in cucumbers Amino phosphonic acid herbicides (model mixture)... 

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