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Processing the RNA Transcript

A primary transcript corresponding to the full length of the gene is first made. This is then chemically modified, and introns (two in the case of /3-globin) are removed by splicing. The mixture of primary transcripts present in the nucleus is known as heterogeneous nuclear RNA (hnRNA). [Pg.497]

Question What modifications are effected in the primary mRNA transcript  [Pg.497]

Polyadenylation results in the addition of a poly (A) tail of 40-200 residues at the 3 end of the transcript. The enzyme responsible for this addition is poly (A) polymerase. The function of the poIy(A) tail is unknown. [Pg.497]

The steps involved in the production of a functional mRNA from a typical eukaryotic gene are shown in Fig. 17-5. For this illustration, we assume that the gene has six introns, which are identified as A-F. Exons are represented as 1-7. Not shown in the diagram is the fact that there is probably a defined order for excision of the individual introns. [Pg.498]

Question What is the reason for the presence of introns in most eukaryotic genes  [Pg.498]


See other pages where Processing the RNA Transcript is mentioned: [Pg.497]    [Pg.270]   


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