Processing Case Study Estimating Abundance of Sample Components

6 Processing Case Study Estimating Abundance of Sample Components 

The imaging data were collected over the spectral range of 1200-2400nm at lOnm increments using a Sapphire NIR-CI system (Spectral Dimensions, Inc., Olney, MD, USA). The size of FOV was 13 x 10mm, each pixel sampling an area of approximately 40 x 40 Um. 

The concentrations of the active ingredients as reported from the manufacturer s label are 37% acetaminophen, 37% aspirin, and 10 % caffeine. The remainder of the tablet mass represents the excipient (binder, disintegrant, and lubricant) materials. Pure acetaminophen, aspirin and caffeine samples are obtained in either tablet form or powder compact and used to obtain reference specua of pure components. 

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