Probucol Quantitative Regression

The adverse effects of probucol have been reviewed (1). As the Probucol Quantitative Regression Swedish Trial (PQRST) showed no improvement in lumen volume of the femoral artery in patients given probucol plus coles-tyramine, as compared with those given colestyramine alone, doubt has been raised about its efficacy (2). 

Walldius Ga, Erikson U, Olsson AG, Bergstrand L, Hadell K, Johansson J, et al. The effect of probucol on femoral atherosclerosis the Probucol Quantitative Regression Swedish Trial (PQRST). Am J Cardiol 1994 74 875-883. 

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