Primary structure and gene analysis

The subunits of FgFi in eukaryotic cells are coded partly by nuclear and partly by organellar genes. Mitochondrial DNA of human cells contains only the gene for subunit 6 [28], but that of yeast cells contains genes for both subunits 6 and 9 of MFq [27,62,63], corresponding to subunits a and c of EFg, respectively. Chloroplast 

DNA contains genes for a, and of CF, [35,36,44], and a [64,44] and c [35,36,44] of CFq, and the and e genes are connected [35,36,44]. The other nuclear genes of FqFi have been extensively studied by the cell fusion technique [65] and gene cloning [66], The in vivo assembly of subunits of FqF, is described in a later chapter of this volume. 

---