Primary constraint targeting

It is worthy of note that the problem solution is such that in each time subinterval, the concentration constraints is met. This implies that, as long as water is available at the right time, it can safely be reused in any of the time subintervals within the concentration interval, i.e. the secondary constraints (concentration) is met in every step of the analysis, and the primary constraints (time) guides the formulation of the final solution (target design network). 

The same hypothetical example was used to illustrate the targeting procedure for a case where concentration is treated as a primary constraints. The problem specification still remains the same as that used Section 12.2.2 (Table 12.2). 

The fresh water target for the first sequence of this system of batch processes is, therefore, 1560 kg. This target is exactly the same as that obtained in Section 12.2.2 when time was taken as the primary constraints. 

Why A primary library can be planned for many purposes. Sometimes the project goal is purely academic, that is, simply to open a new combinatorial synthetic route and to report it. This respectable option allows complete freedom to prepare any primary library, with no constraints dictated by parameters such as application, cost, or resources. We will not comment further upon this approach in this section. More often, though, a primary library is prepared as a source of relevant active molecules on various biological targets. This obviously necessitates the availability of several robust and reliable HTS assays for these targets, as well as the synthetic resources, the analytical resources, and the instrumentation to ensure the successful synthesis and analytical characterization of the library. 

In the case of secondary target energy-dispersive systems, while the geometric constraints are still less severe than for the wavelength system, they are much more critical than in the primary systems. Where practicable, the best solution for the handling of limited amounts of material is invariably found in one of the specialized spectrometer systems, of which total reflection x-ray spectrometry is a good example. 

---