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Priftin - Rifapentine

Priftin rifapentine Hylutin, Megace, Micronor, Nor-QD, Norlutate,... [Pg.673]

Rifapentine (Priftin) [Antibiotic/Antitubercular Agent] Uses Pulm TB Action X DNA-dependent RNA polymerase. Dose Intensive phase ... [Pg.274]

Oral 150, 300 mg capsules Parenteral 600 mg powder for IV injection Rifapentine (Priftin)... [Pg.1054]

Rifampin (Rifadin, Rimactane), and similar agents such as rifabutin (Mycobutin) and rifapentine (Priftin), directly impair DNA replication by binding to and inhibiting the DNA-dependent RNA polymerase enzyme in susceptible bacteria. This enzyme initiates the replication of genetic material by generating the formation of RNA strands from the DNA template. By inhibiting this enzyme, rifampin blocks RNA chain synthesis and subsequent replication of the nucleic acid code in bacterial cells. [Pg.512]

Rifapentine (Priftin) has a longer half-life than rifampin and rifabutin, which allows once-weekly dosing. Compared to rifabutin and rifampin, it is intermediate in its induction of CYPs. Its use in the treatment of tuberculosis in HIV-infected patients was associated with the selection of rifa-mycin resistance rifabutin is therefore preferred in this situation. [Pg.621]

See other pages where Priftin - Rifapentine is mentioned: [Pg.50]    [Pg.36]    [Pg.35]    [Pg.510]    [Pg.1103]    [Pg.676]    [Pg.621]    [Pg.1754]   


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