Preparative layer trends

One of trends of development of thin-layer chromatography implies that replacement of aqueous-organic eluents by micellar surfactants solution. This is reduces the toxicity, flammability, environmental contamination and cost of the mobile phases, reduce sample prepar ation in some cases. 

Fitting into the trend towards improvement of the availability and simplification the preparation of biocatalytic layers for biosensors, the use of crude materials has been explored. Arnold and coworkers investigated the feasibility of employing Jack bean meal in a urea sensor (Arnold and Glaizer, 1984) and rabbit muscle acetone powder in a sensor for adenosine monophosphate (Fiocchi and Arnold, 1984). Both sensors turned out to be serious contenders with the appropriate enzyme electrodes with respect to lifetime and slope of the calibration curves. Other parameters, such as response time and linear range, were quite similar. 

Another important consideration is the fact that most EPs can be prepared electrochemically. The very nature of this mode of deposition guarantees fine control over the deposition conditions. The control over the final thickness of the material, deposition in a small and geometrically complex area, simultaneous deposition and post-deposition conditioning of several layers, and electropolymerization of unusual materials, are important facets that again complement the trend towards miniaturization and... 

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