Preparation of the Key Protected Octasaccharide

Final comments Such an overall strategy can be utilized to synthesize a variety of oligosaccharides of the polylactosamine type, with additional possible L-fucose residues. It is thus of general interest and can be considered as a classic. Many considerations in this synthesis have also been delineated by other groups, and this achievement reflects a nice strategical manipulation of many interesting observations done over the years. 

The aim of this chapter was to convince the reader that the chemical organic synthesis in solution of oligosaccharides of any complexity is now feasible. More than 

Tailler, J.-C. Jacquinet, J.-M. Beau, XVlth Intern. Carbohydr. Symp., Paris 1992, A298 b) D. Tailler, J.-C. Jacquinet, J.-M. Beau. J. Chem. Soc, Chem. Commun. 1994, 1827. 

Ikeshita, A. Sakamoto, Y. Nakahara, Y. Makahara, T. Ogawa. Tetrahedron Lett., 1994, 3123. 

Necciari, R. Cariou, A.M. Gabaig, G. KiefTer, J. Dickinson, G. Lamond, H. Moelker, T. Mant, H. Magnani, Thromb. Haemost., 1995, 74, 1468. 

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