Preparation of Carboxypyrazines

Preparations of carboxypyrazines (1) by primary synthesis have been described in Sections II.lA-C, II.IF, II.II, II.2, II.4, II.5, and II.7. Additional data on the hydrolysis of some pteridines to hydroxylated carboxypyrazines and amino carboxypyrazines are given in Sections VI.1A and VIII.1A(1), respectively. 

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