Pregnancy hypothyroidism therapy

Ovarian enlargement, hemoperitoneum, febrile reactions, multiple pregnancies, hypersensitivity Failure to respond to therapy due to development of antibodies, hypothyroidism, insulin resistance, swelling of the joints, joint and/or muscle pain Same as somatropin... 

Low LC, Ratcliffe WA, Alexander WD. Intrauterine hypothyroidism due to antithyroid-drug therapy for thyrotoxicosis during pregnancy. Lancet 1978 2(8085) 370-1. 

Other treatment options, besides thioamide therapy, involve RAI. The iodine 131 isotope is taken up by the thyroid gland and the radioactivity destroys the gland. RAI is safe, pain free, easy to administer, and very effective. RAI may result in euthyroidism but more frequently results in hypothyroidism requiring lifelong levothyroxine supplementation. RAI should never be given during pregnancy since it crosses the placenta. 

Thus, a TSH measurement higher than these values might be indicative of hypothyroidism during pregnancy. Whether this level should be used in decision-making for initiating T4 therapy, especially in women with thyroid antibodies positive, is a controversial point (GUnoer and Abalovich, 2007). 

Severe febrile illnesses, pregnancy, myxedema (condition resulting from hypothyroidism), and cancer therapies are conditions contributing to temporary hair loss. 

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