Preferential anatomic site

As one miglit expect. c. posure to a chemical compels a response by the human body. The body responds to a chemical with physiological (metabolic) processes in order to absorb, distribute, store, transform, or eliminate tliat chemical. To become a chemical health hazard, tlie chemical or tlie transformation of that chemical by the body must reach a target organ for a sufficient length of time and at a sufficient concentration to produce toxic effects. A target organ is tlic preferential anatomical site for the expression of toxic effects by a chemical substance in tlie human body. 

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