Predictions from Model Ecosystem Microcosm and Mesocosm Data

3 Predictions from Model Ecosystem (Microcosm and Mesocosm) Data 

Predictions of PNECs or EQSs based on mesocosm or microcosm chronic NOEC data, if available, are probably of greatest reliability, and such data can be used as a benchmark for comparison with other EQS derivation methods (see Section 4.7). 

After analyzing data sets for 16 pesticides, as well as assessing evidence from the open literature, Brock et al. (2006, p. 25) showed that 

The median acute HC5 value is lower than the effect class 2 concentration observed in microcosm and mesocosm experiments treated once with a pesticide. The corresponding lower-limit HC5 value was, with high certainty, lower than reported effect class 1 

In other words, SSD predictions tend toward overprotection for acute effects in 

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