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Potential use of fluorinated monolayers in biological sciences

The examples given here involve lung surfactant replacement compositions and surfactant systems used for 2D protein crystallization. Other potential systems include direct, reverse and multiple emulsions for drug and gene delivery, as well as micro- and nano-sized gas bubbles for O2 delivery and diagnosis [3, 4] [Pg.186]

With the objective of designing new compositions of synthetic substitutes for the native lung surfactant, it is desirable to control the physical state and properties of dipalmitoylphosphatidylcholine (DPPC) spread at the air/water interface. DPPC is the main component of the native lung surfactant, which also comprises a complex mixture of lipids and specific proteins [62], Langmuir monolayers provide a model of the air/alveolar interface that is widely used for assessing the properties of lung surfactant replacement compositions. [Pg.186]

The mixing behavior of 10-(perfluorohexyl)-decanol and DPPC in Langmuir monolayers has recently been reported, showing partial miscibility, especially at low surface pressure [67], 10-(perfluorohexyl)-Decanol was studied because it is a fluorinated analog of hexadecanol, which has been used in synthetic lung surfactant compositions. [Pg.186]

However, it is known that carboxylic perfluorinated acids, in particular perfluorooctanoic acid, accumulate in the living organisms and are environmentally persistent [68], [Pg.187]


See other pages where Potential use of fluorinated monolayers in biological sciences is mentioned: [Pg.178]    [Pg.186]   


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Biological sciences

Biology sciences

In potential use

Of monolayer

Potentiation, fluorine

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