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Potential Replacements for the Active Pharmacological Control Treatment Arm

3 Potential Replacements for the Active Pharmacological Control Treatment Arm [Pg.152]

Several potential replacements of the active pharmacological control treatment arm in a TQT study with another means of establishing assay sensitivity have been discussed in the literature. One example is the detection of food-indnced QTc shortening (Taubel et al. 2012 Hnatkova et al. 2014). [Pg.152]

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Activation control

Activator Replacement

Active control arm

Active controls

Arms control

Controlled potential

Controlling activities

Pharmacologic activity

Pharmacological treatments

Pharmacologically active

Pharmacology activity

Potential control

Potential controlled activity

The Treatments