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Potassium channels molecular correlation

This review focuses on the recent discovery and development of chemical entities targeting the Kvl.5 potassium channel subunit for the treatment of atrial arrhythmias. This strategy is based on the expression of the ultrarapidly activating delayed rectifier potassium current, /Run in atria but not ventricles of humans, and on the molecular characterization of the Kvl.5 channel subunit as a structural correlate of JRur [1-6]. Although no perfectly selective Kvl.5... [Pg.145]

BRL-32872 is a new anti-arrhythmic drug with balanced class-III and class-IV actions, which blocks the rapid component of the cardiac delayed rectifier potassium channel IK(r) and its molecular correlate... [Pg.767]

See other pages where Potassium channels molecular correlation is mentioned: [Pg.350]    [Pg.44]    [Pg.507]    [Pg.314]    [Pg.54]    [Pg.145]    [Pg.143]    [Pg.144]   
See also in sourсe #XX -- [ Pg.177 , Pg.179 ]



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Channels, molecular

Potassium channels

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