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Postsynaptic GABAb receptors

Structural and Functional Diversity Between Presynaptic and Postsynaptic GABAb Receptors... [Pg.396]

In the spinal cord GABA can also activate the G-protein-linked GABAb receptor, also found pre- and postsynaptically. Baclofen modulation of nociceptive transmission is seen under inflammatory conditions in animals but in humans the drug appears to lack any analgesic effect. [Pg.466]

GABA receptors are divided into two main types GABAa and GABAB. inhibitory postsynaptic potentials in many areas of the brain have a fast and slow component. The fast component is mediated by GABAa receptors and the slow component by GABAB receptors. The difference in kinetics stems from the differences in coupling of the receptors to ion channels. GABAa... [Pg.463]

The most pronounced effect of paired-pulse depression occurs at an interstimulus interval of 200 ms [64]. The impact of paired-pulse depression is significantly larger for the GABAb receptor mediated inhibitory postsynaptic currents. The IPSCb evoked by the second stimulus was depressed by 62 8%, whereas the IPSCa evoked by the second stimulus was depressed by 37 4% as shown in Fig. 10 [64]. [Pg.261]

See other pages where Postsynaptic GABAb receptors is mentioned: [Pg.519]    [Pg.242]    [Pg.244]    [Pg.135]    [Pg.138]    [Pg.373]    [Pg.519]    [Pg.253]    [Pg.255]    [Pg.256]    [Pg.258]    [Pg.263]    [Pg.1207]    [Pg.519]    [Pg.242]    [Pg.244]    [Pg.135]    [Pg.138]    [Pg.373]    [Pg.519]    [Pg.253]    [Pg.255]    [Pg.256]    [Pg.258]    [Pg.263]    [Pg.1207]    [Pg.516]    [Pg.516]    [Pg.798]    [Pg.233]    [Pg.246]    [Pg.293]    [Pg.35]    [Pg.134]    [Pg.71]    [Pg.268]    [Pg.346]    [Pg.25]    [Pg.21]    [Pg.463]    [Pg.511]    [Pg.724]    [Pg.391]    [Pg.436]    [Pg.497]    [Pg.195]    [Pg.460]    [Pg.486]    [Pg.516]    [Pg.516]    [Pg.798]    [Pg.388]    [Pg.432]    [Pg.483]    [Pg.469]    [Pg.152]    [Pg.261]    [Pg.264]    [Pg.114]   
See also in sourсe #XX -- [ Pg.253 , Pg.255 , Pg.256 , Pg.258 , Pg.263 ]



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GABAb

GABAb receptors

Postsynaptic receptors

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