Postinfectious autoimmune

Finally, it is tempting to speculate that in SC and postinfectious forms of TS the functional activity of the MSP neurons of the matrix is differentially impaired as a result of the autoimmune response. Indeed, preliminary data suggest that either bilateral striatal infusion into rats of antineuronal antibodies from TS patients or the immunization of mice with rat striatal homogenates may produce animal models of TS complete with stereotypical movements and audible vocalizations (Hallett et al., 2000 Hoffman and Lipkin, 2000). One plausible hypothesis is that the antineural antibodies found in a subset of TS patients may modulate synaptic transmission and alter the balance between the striosomal and matrisomal compartments of the striatum (Leckman and Riddle, 2000). 

Autoimmune haemolytic anaemia (AIHA). Acquired haemolytic anaemia mediated by autoantibodies against antigens on the organism s own red cell membrane. Autoimmune haemolytic anaemia may be idiopathic, secondary to lymphoproliferative, autoimmune (e.g. systemic lupus erythematosus), or chronic inflammatory disorders, postinfectious or drug-induced. See also -anaemia, cold autoantibody type, warm autoantibody type, -drug-induced immune haemolytic anaemia. 

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