Portieria homemannii

Puglisi, M. P. and Paul, V. J., Intraspecific variation in the red algae Portieria homemannii monot-erpene concentrations are not influenced by nitrogen or phosphorus enrichment, Mar. Biol., 128, 161, 1997. 

Matlock, D. B., Ginsburg, D. W., and Paul, V. J., Spatial variability in secondary metabolite production by the tropical red algae Portieria homemannii, Hydrobiologia, 398/399, 267, 1999. 

Barahona LF and Rorrer GL, Isolation of halogenated monoterpenes from bioreac-tor-cultured microplantlets of the macrophytic red algae Ochtodes secundiramea and Portieria homemannii, J. Nat. Prod., 66, 743, 2003. 

CioHijBrjCla, Mr 401.39, mp. 49-50 C, [ajp +206 (CH2CI2). A cytotoxic antitumor compound from the red alga Portieria homemannii. H. shows selective cytotoxicity against different tumor cell lines. 

Halomon is a polyhalogenated monoterpene isolated from the red alga Portieria homemannii, which has cytotoxic properties (see Chapter 13). 

Several other polyhalogenated structures with the skeleton of ochtodane (l,l-dimethyl-3-ethyl-cyclohexane) were obtained from Portieria homemannii (Kuniyoshi et al, 2003). Although the halogenated monoterpene compositions of these two species vary with the place of harvest, this difference is no more than that which occurs by growing tissue in a photobioreactor (Barahona and Rorrer, 2003). 

Egorin, M.J., Sentz, D.L., Rosen, D.M., Ballesteros, M.F., Kearns, C. M., Callery, P.S., and Eiseman, J.L. (1996) Plasma pharmacokinetics, bioavailability and tissue distribution in CD2F1 mice of halomon, an antitumor halogenated monoterpene isolated from red alga Portieria homemannii. Cancer Chemother. Pharmacol., 39, 51-60. 

Kuniyoshi, M., Oshiro, N., Miono, T, and Higa, T. (2003) Halogenated monoterpenes having a cydohexadienone from the red alga Portieria homemannii. J. Chin. Chem. Soc. (Taipei), 50,167-170. 

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